SeeCell - Digital Lensless Holographic Microscope
Precise, Wide, 3D Imaging of Cells at Hundreth of the Price
SeeCell - Digital Lensless Holographic Microscope
Precise, Wide, 3D Imaging of Cells at Hundreth of the Price
WHAT IS "LENSLESS" MICROSCOPY?
Lensless microscope imaging is a novel microscope imaging technology that can simultaneously realize large field of view, high resolution, and label-free imaging compared with traditional lens-based imaging technology. Due to the limitation of its optical design principle, the spatial bandwidth of traditional optical microscopes is generally always limited to megapixels, which can not take into account the high resolution and large field of view at the same time. On the other hand, the complex optical system also makes microscopes increasingly expensive, bulky, complicated and difficult to maintain, which greatly limits their popularization and application. Compared with the traditional lens imaging technology, lensless microimaging technology does not require an imaging lens for focusing imaging. This has significant advantages in simplifying the imaging system and reducing the cost of the microimaging system, and is of great scientific significance in observing the cell growth process, spore screening for rice blast disease, and other applications. As a measurement technique based on phase recovery (without phase recovery in the special case of direct projection), lensless microimaging has the advantages of large field of view, high resolution, no need for labeling, low cost, good portability, and three-dimensional imaging, etc. It is expected to expand the boundaries of the traditional microimaging technology, and to become a new type of fast and portable Point-of-Care Testing (POCT). Point-of-Care (POCT) tool.
Learn More
Find out the imaging procedure that turns a cell into 3D images in seconds. Learn more about the algorithm and the optical path design.
Looking Bigger and with More Detail
Traditional optical microscopes are limited by trade-off between field of view and resolution. Red: larger field of view and lower resolution. Green: smaller field of view but higher resolution.
Key Advantages
Label-Free Imaging
3-D Imaging
Wide field of view (FOV): FOV = 36.2mm²; 100 times larger than traditional optical microscopes
High resolution: pixel size = 1.4μm
Cost-effective design: $500; thousandth of existing 3D microscopes
Function
Quantitative phase reconstruction
Large volume imaging
360 ° phase gradient imaging
Cell count analysis
Dynamic 3D imaging
Medical Applications
Cancer and disease diagnosis
Water-quality monitoring
Microbial viability testing
3-D motion tracking
Red blood cell characterization
Cancerous cells screening
Cell counting.
Examples
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CCell: Digital Lensless Holographic Microscope
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